By Nancy Hepp, MS, CancerChoices Program Manager and Lead Researcher, with contributions from Miki Scheidel, CancerChoices Co-Founder and Creative Director.
We expect that you’ve already heard that you should eat better, exercise more, get enough sleep, manage your weight, stop smoking, and other similar advice from your doctor and others. Did you know that being active in your wellness by building these practices and habits can improve your outcomes with conventional cancer treatments such as chemotherapy, surgery, and immunotherapy?
Your ability to recover from surgery, chemotherapy, or radiotherapy is typically better if you have better nutrition, more muscle mass, less excess body weight, no tobacco use, and fewer disruptions to hormone balance, blood sugar levels, and immune function. Not only are these goals “good for you” in an abstract sense—they may make your life better in ways that you will notice during and after cancer treatment. Shorter hospital stays after surgery. Less sleep disruption. Less fatigue. Less pain. And all without the side effects and the high price tags that many medications have.
Your survival after a cancer diagnosis is also affected by these habits and practices. A better diet, more exercise, better sleep, and better stress management are all linked to longer survival. Even your response to conventional treatments can depend in part on your health status. The composition of your microbiome—your personal collection of microbes living on and in your body—may influence how well you respond to immunotherapy, for example.1-5 What you eat has a direct and rapid effect on the composition of your microbiome. Exercise, smoking, obesity, and stress are also linked to your microbiome.
You can be active in your wellness after a cancer diagnosis, starting with 7 Healing Practices. These are known to improve outcomes including survival, risk of recurrence, or symptoms and side effects from cancer or its treatment. Many directly influence your body terrain—your internal environment of hormones, inflammation, blood sugar, oxidation, microbes, and more—which is tied to cancer growth and spread.
At the center of these practices is Exploring What Matters Now. When diagnosed with cancer, your insights related to this exploration may be your best guide to the treatments you wish to take, your priorities in life, and how you want to live. Once you have some clarity with what matters now for you (although your answers may shift over time), you can start looking at the other six practices. As Co-Founder of CancerChoices Michael Lerner advises, “Do what you are drawn to. No practice is healing unless it feels healing.”
The CancerChoices website offers a description of each of these practices, the evidence supporting them, and what experts recommend. We provide tips and links to trusted resources such as apps and groups and websites for making changes to support you as you begin and maintain changes. For some practices, such as Sleeping Well and Managing Stress, we describe therapies that can help you achieve these practices.
If you’re not ready for change now, we’ll be there later without any judgment whenever you are ready to begin or if you stumble a bit after getting started. You’re in the driver’s seat. We’re ready to navigate for you. At your time and pace.
- Aghamajidi A, Maleki Vareki S. The effect of the gut microbiota on systemic and anti-tumor immunity and response to systemic therapy against cancer. Cancers (Basel). 2022 Jul 22;14(15):3563.
- Hu Y, Li J et al. CAR-T cell therapy-related cytokine release syndrome and therapeutic response is modulated by the gut microbiome in hematologic malignancies. Nature Communications. 2022 Sep 9;13(1):5313.
- Wang F, He MM et al. Regorafenib plus toripalimab in patients with metastatic colorectal cancer: a phase Ib/II clinical trial and gut microbiome analysis. Cell Reports. Medicine. 2021 Aug 27;2(9):100383.
- Baruch EN, Youngster I et al. Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients. Science. 2021 Feb 5;371(6529):602-609.
- Hopkins AM, Kichenadasse G, Karapetis CS, Rowland A, Sorich MJ. Concomitant antibiotic use and survival in urothelial carcinoma treated with atezolizumab. European Urology. 2020 Oct;78(4):540-543.