Research at the CHI
The CHI is an innovative research centre and integrative health care clinic. Our research is led by our CEO who also serves as the Executive Director of Integrative Oncology for the Canadian College of Naturopathic Medicine (CCNM). Our research is jointly run with CCNM and other research partners to conduct clinical trials, observational studies, and synthesis research relating to complementary and integrative medicine for cancer.
Research Summaries for Integrative Therapies
To support informed decision-making, we are committed to developing evidence-based Research Summaries for Integrative Therapies, also called monographs, to summarize the safety and effectiveness of commonly used complementary therapies and natural health products in the context of cancer.
Here you will find the Research Summaries we have published to date. There are patient versions (a quick summary) as well as health professional versions (a longer, more detailed summary). We do our best to keep the monographs up to date, however be aware the monographs only encompass information known at the time of writing.
Patient Versions
Mistletoe (Viscum album) last updated January 2020
Intravenous Vitamin C last updated August 2019
Coriolus Versicolor (Turkey Tail Mushroom) last updated October 2015
Dichloroacetate (DCA) last updated July 2015
Alpha Lipoic Acid (ALA) last updated March 2014
Green Tea (Camellia sinensis) last updated February 2014
Acupuncture last updated February 2014
Black Cohosh for Breast Cancer last updated February 2014
Flax for Breast Cancer last updated February 2014
Red Clover for Breast Cancer last updated February 2014
Soy for Breast Cancer last updated February 2014
Vitamin D for Breast Cancer last updated February 2014
Health Professional Versions
Mistletoe (Viscum album) last updated January 2020
Intravenous Vitamin C last updated July 2019
Coriolus Versicolor (Turkey Tail Mushroom) last updated October 2015
Acupuncture last updated February 2014
Alpha Lipoic Acid (ALA) last updated January 2014
Green Tea (Camellia sinensis) last updated January 2014
Dichloroacetate (DCA) last updated October 2013
Black Cohosh for Breast Cancer last updated August 2013
Flax for Breast Cancer last updated August 2013
Red Clover for Breast Cancer last updated August 2013
Soy for Breast Cancer last updated August 2013
Vitamin D for Breast Cancer last updated August 2013
Active and Ongoing Research Studies
Study Status: Recruiting
The OICC and CCNM research have partnered with the Ottawa Hospital Research Institute to create the first randomized clinical trial in North America studying the real-world effects of integrative care guided by a naturopathic doctor (ND) in patients with lung and gastro-esophageal cancers. Patients in this study will receive either recommendations from an ND alongside their conventional treatments (integrative group) or conventional care alone (control group). Outcome measures include quality of life, qualitative experience, adverse events, blood markers, and survival outcomes. Together with other clinics across Ontario, the study team will recruit and follow 350 participants over the next 10 years.
Clinical trials identifier: NCT02845479
Study Status: Recruiting
The OICC research team is evaluating the Inspire Now program – a support program for people living with lung cancer. 50 program participants will be recruited in order to determine if the program has an effect on the quality of life, specific concerns, and general wellbeing of the participants. Researchers are utilizing quantitative and qualitative methods to track participant experiences throughout the program. This study is currently active and recruiting with each program session; all who are eligible for the program are able to participate in this research study.
Study Status: Closed to Recruitment
Through a partnership with the Ottawa Hospital Research Institute, the OICC and CCNM research have conducted the first randomized, placebo-controlled clinical trial studying the effects of melatonin in surgically resected lung cancer. With 8 sites across Canada, we were able to enrol 709 participants over a period of 10 years. Measured outcomes included the incidence of cancer recurrence, quality of life, sleep, fatigue, adverse events, and survival outcomes. This study is now closed to recruitment, and the manuscript is currently submitted for publication.
Clinical trials identifier: NCT00668707
Study Status: Closed to Recruitment
Working in partnership with Bastyr University, the OICC and CCNM research have initiated a North American study to explore the impact of advanced integrative care delivered by NDs for patients with advanced breast, colorectal, ovarian, and pancreatic cancer. 12 clinics across NA have recruited patients to participate in this prospective observational study to describe quality of life, costs, qualitative experiences, and survival outcomes. Recruitment is now complete, with 400 patients enrolled. Participants will continue to be followed until 2022.
Clinical trials identifier: NCT02494037
Study Status: Closed to Recruitment
This study aims to explore the effectiveness of the yoga therapy program offered at the OICC for improving autonomic nervous system functioning and patient-reported outcomes among cancer survivors. Anecdotal evidence suggests yoga therapy can help lower stress, increase body awareness, and feelings of empowerment; however, the effectiveness of this intervention in promoting autonomic nervous system functioning and improving patient-reported outcomes has not been empirically evaluated. Specifically, the study seeks to determine if there are changes in self-reported and objective autonomic nervous system functioning in cancer survivors before and after a one-on-one yoga therapy session, and after a 6 week group yoga therapy program, and whether these changes are maintained for 6 weeks after completion of the yoga program. This study is a collaborative effort between the Ottawa Integrative Cancer Center and the University of Ottawa.
Study Status: Closed to Recruitment
The OICC is a sub-site for a collaborative research study with InspireHealth in British Columbia. The purpose of the clinical trial is to study the therapeutic effect and safety of high-dose vitamin D supplementation in people with stage 4 (metastatic) colorectal cancer. Participants are randomized to high-dose vitamin D treatment or a control group. Recruitment for this study is completed.
Clinical trials identifier: NCT01150877
Research Team
Dr. Dugald Seely, ND, M.Sc.
Founder & CEO
As founder and CEO of the Centre for Health Innovation, Dr. Dugald Seely ND leads the research department and is pioneering an innovative model of cancer care based on the provision and study of scientifically grounded, evidence-informed complementary medicine. With the establishment of the first integrative cancer care and research centre in Eastern Canada, Dr. Seely and his team are providing whole-person integrative care to people living with cancer and conducting relevant research in the realm of integrative medicine.
Dr. Seely completed his MSc in cancer research at the University of Toronto and is a Fellow of the American Board of Naturopathic Oncology (FABNO). As a clinician scientist, Dr. Seely has been awarded competitive grant and trainee funding from the Lotte and John Hecht Memorial Foundation, CIHR, CBCRA, the SickKids Foundation, and the Gateway for Cancer Research. In addition to clinical research, Dr. Seely has conducted and supervised dozens of synthesis reviews and meta-analyses with the goal of building on the growing body of evidence that supports integrative oncology.
Dr. Seely serves as executive director of research & clinical epidemiology at the Canadian College of Naturopathic Medicine, is an adjunct professor with the Faculty of Medicine at the University of Ottawa, and is an affiliate investigator with the Ottawa Hospital Research Institute. Dr. Seely is section editor for Integrative Oncology with the journal, Current Oncology, and is the President of the Oncology Association of Naturopathic Physicians (OncANP). Dr. Seely has published over 70 Medline indexed peer-reviewed publications and speaks at national and international conferences with the goal of expanding consciousness towards a more proactive model of healthcare. In 2017 Dr. Seely was the recipient of the Dr. Rogers Prize for excellence in Complementary and Alternative Medicine.
Outside of professional life, Dugald likes to spend time on outdoor adventures with his family traveling, hiking and biking or indoors playing all manner of card and board games.
Dr. Ellen Conte (McDonell), ND
Naturopathic Doctor & Research Associate
Dr. Ellen Conte (McDonell), ND is a naturopathic doctor and researcher focusing on supportive cancer care and general health concerns. In her clinical practice, Ellen uses evidence-informed therapies to help manage symptoms and side effects of cancer and cancer treatment, provide adjunctive care for the management and prevention of cancer, and optimize overall health. Ellen primarily utilizes nutrition, nutritional supplementation, exercise counseling, herbal medicine, and lifestyle counseling to support people. Through research at the CHI, Ellen works to improve cancer outcomes by studying the effects of a complementary and integrative approach to cancer care. Her work has been published in peer-reviewed medical journals and presented at conferences.
Ellen obtained her doctor of naturopathy from The Canadian College of Naturopathic Medicine (CCNM), and has a degree in biochemistry from the University of Ottawa. She completed an internship in adjunctive cancer care while at CCNM, completed a two year cancer-focused residency through CCNM, and regularly attends oncology-focused medical conferences. Ellen is an active member of the naturopathic medical community; she is Chair of the Oncology Association of Naturopathic Physician's Research Committee, contributes to writing and peer-review of naturopathic medical publications including the Natural Medicine Journal and the Vital Link, and previously served as President of the Naturopathic Students Union. Ellen is a member of the Oncology Association of Naturopathic Physicians, Canadian Association of Naturopathic Doctors, Ontario Association of Naturopathic Doctors, and is registered with the College of Naturopaths of Ontario.
Although Ellen is a Haligonian who misses the ocean, she has developed a love for Ottawa and in particular the active outdoor community. An avid runner and triathlete, when not at work she’s usually outside rain or shine enjoying the river, canal, and trails in the area.
Mark Legacy
Clinical Research Assistant
Mark is a clinical researcher working to improve patient care by looking into complementary treatments that embrace a holistic and integrative approach to traditional practices at most hospitals. Mark developed an early interest in research while completing his degree in biomedical sciences at the University of Ottawa. Now a full-time researcher for the CHI, Mark collaborates with many different institutions across Canada and North America to design and coordinate clinical trials and observational studies. Mark is also an employee of The Ottawa Hospital, working closely and often collaboratively with the Thoracic Surgery Research Team at the Ottawa Hospital Research Institute. With most of his research being the first of its kind, Mark and his colleagues are eager to provide new insights to the field of integrative oncology.
Dr. Mohamed El Sayed, MD (Egypt), M.Sc., PhD, ND
Research Assistant
In addition to being a licensed naturopathic doctor, Mohamed is a foreign trained medical doctor from Egypt holding both M.Sc. and PhD degrees in radiation oncology. He has held clinical, research, and academic positions in oncology for nearly 20 years. Mohamed has published 26 journal articles on various cancer-related topics and is a reviewer for four international peer-reviewed oncology journals.
Rebecca Vanschyndel
Qualitative Research Consultant
Rebecca completed the Masters Program in Health Sciences, Occupational Therapy at the University of Ottawa. She has practiced as an Occupational Therapist in the community for many years. She is currently a PhD candidate at the University of Ottawa in the Health Sciences, Rehabilitation Sciences Program. Rebecca is a Qualitative Research Consultant with the Centre for Health Innovation.
Dr. Athanasios Psihogios, ND (Inactive)
Research Assistant
Dr. Athanasios (Thanasi) Psihogios, ND (Inactive), is an integrative oncology researcher dedicated to advancing this pioneer-type field in order to provide patients with safe and efficacious therapy options. Currently, in order to expand his research abilities and knowledge, Thanasi is completing a Master of Public Health degree. In addition to health research, with his background and passion for philosophy, Thanasi is particularly interested in the reasoning and modes of thinking behind peoples’ decision to use integrative medicine.
Since 2017, currently a senior research assistant, Thanasi has worked with the Oncology Association of Naturopathic Physicians (OncANP) on the Knowledge in Naturopathic Oncology Website (KNOW) database. This project is dedicated to collecting, summarizing and critically appraising integrative oncology research to be utilized by clinicians to make evidence-informed clinical decisions. Prior to becoming a CHI research resident, Thanasi was a volunteer research assistant with the clinic, with his most notable project involvement being the Integrative Pediatric Oncology Program (IPOP) practice survey. His work on this project, pertaining to practice trends in naturopathic pediatric cancer care, has been published in a peer-reviewed medical journal and presented at a conference.
Thanasi graduated from the Canadian College of Naturopathic Medicine with a Doctor of Naturopathy degree. He received a BA from the University of Ottawa, with a focus on both health science and philosophy.
Dr. Erica Rizzolo, ND
Naturopthic Doctor & Research Assistant
Dr. Erica Rizzolo, ND is a licensed naturopathic doctor and research assistant at the Centre for Health Innovation (CHI). Prior to naturopathic medical school, she completed her undergraduate degree in Kinesiology at McMaster University, where she also worked as a personal trainer. Erica is an active member of the research committee for the Oncology Association of Naturopathic Physicians (OncANP).
In practice, Erica focuses on supporting people affected by cancer; from initial diagnosis through chemotherapy, surgery, and preventing recurrence. She helps patients manage side effects, energy levels and mental health throughout all stages of their cancer journey. In addition to supportive cancer care, Erica has a clinical focus on mental health concerns, Inflammatory Bowel Disease (IBD), and sports nutrition.
Dr. Rizzolo’s clinical approach is evidence-based and patient-centred. Erica enjoys working with patients to create realistic and sustainable treatment plans, through the use of nutrition, physical activity, supplements, herbal medicine and counselling. Dr. Rizzolo’s care is focused on supportive cancer care, digestive health, inflammatory bowel disease (IBD), stress management, anxiety, eating disorders, and sports nutrition. Please feel free to reach out to book a free 15-minute meet and greet, or initial visit today.
Research Publications
Browse by Year
Intervention Development Process for a Pragmatic Randomized Controlled Trial: The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial
Authors: Seely, D., Ennis, J.E., McDonell, E., et al.
Publication: Journal of Alternative and Complementary Medicine
Citedate: March 19, 2019
Citation: J Altern Complement Med. 2019;25(S1):S112-S123.
PMID: 30870012
A systematic review of acupuncture for chemotherapy-induced peripheral neuropathy
Authors: Li, K., Giustini, D., & Seely, D.
Publication: Current Oncology
Citedate: April 1, 2019
Citation: Curr Oncol. 2019 Apr;26(2):e147-e154.
PMID: 31043820
Chapter 5 of Women's Health and Complementary and Integrative Medicine: Women's cancers and complementary and integrative medicine
Authors: Schloss, J., Alschuler, L., & McDonell, E.
Citedate: 2019
Citation: In: Adams J, ed. Women's Health and Complementary and Integrative Medicine. Abingdon, UK: Routledge; 2019: 63-76
Editorial: The Oncology Association of Naturopathic Physicians Principles of Care Guidelines
Authors: Seely, D., & Verma, S.
Publication: Current Oncology
Citedate: February 1, 2019
Citation: Curr Oncol. 2019. Vol 26, No 1.
PMID: 30853791
Integrative Oncology: International Perspectives
Authors: Grant, S.J., Hunter, J., Seely, D., Balneaves, L.G., Rossi, E., & Bao, T.
Publication: Integrative Cancer Therapies
Citedate: January 30, 2019
Citation: Integr Cancer Ther. 2019. Jan-Dec;18
PMID: 30791736
Milk thistle (Silybum marianum)
Authors: McDonell, E. Green, J., & Kalisch, A.
Publication: CAM-Cancer Consortium
Citadate: January 29, 2018
An N-of-1 Feasibility Study of Homeopathic Treatment for Fatigue in Patients Receiving Chemotherapy
Authors: Brulé, D., Balon, .J., Zhao, L., & Seely, D.
Publication: Homeopathy
Citedate: May 7, 2018
Citation: Homeopathy. 2018 Aug;107(3):196-201.
PMID: 29734461
Intravenous vitamin C in the supportive care of cancer patients: a review and rational approach
Authors: Klimant, E., Wright, H., D. Rubin, Seely, D. & Markman, M.
Publication: Current Oncology
Citedate: Monday, April 30, 2018
Citation: Curr Oncol. 2018 Apr; 25(2): 139–148.
PMID: 29719430
Boswellia spp
Authors: McDonell, E., Dennert, G., & CAM-Cancer Consortium.
Publication: CAM-Cancer Consortium.
Citedate: September 11, 2018
Naturopathic Oncology Care for Thoracic Cancers: A Practice Survey
Authors: Seely, D., Ennis J.K., McDonell, E., & Zhao. L.
Publication: Integrative Cancer Therapies
Citedate: Monday, December 18, 2017
Citation: Integr Cancer Ther. 2018;17(3).
PMID: 29558830
Personal goals of women recently diagnosed with breast cancer: Protocol for a cohort study
Authors: Chow, A.J., Fergusson, D.A., Seely, D., Young, S., Pitman, A., Ennis, J., Asad, S., Presseau, J.
Publication: University of Ottawa Journal of Medicine
Citedate: Dec 18, 2017
Citation: UOJM. Dec 2017; 7(2):34-41.
Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment
Authors: Greenlee, H., DuPont-Reyes, M.J., Balneaves, L.G., Carlson, L., Cohen, M.R., Deng, G., Johnson, J.A., Mumber, M., Seely, D., Zick, S.M., Boyce, L.M., & Tripathy, D.
Publication: A Cancer Journal for Clinicians
Citedate: April 24, 2017
Citation:CA Cancer J Clin. 67(3):194-232.
PMID: 28436999
Qualitative assessment of information and decision support needs for managing menopausal symptoms after breast cancer
Authors: Balneaves, L.G., Panagiotoglou, D., Brazier, A.S., Lambert, L.K., Porcino, A., Forbes, M., Van Patten, C., Truant, T.L., Seely, D., & Stacey, D.
Publication: Supportive Care in Cancer
Citedate: June 8, 2016
Citation: Support Care Cancer. 2016 Nov;24(11):4567-75.
PMID: 27278271
Fish-Derived Omega-3 Fatty Acids and Prostate Cancer: A Systematic Review
Authors: Aucoin, M. , Cooley, K., Knee, C., Fritz, H., Balneaves, L.G.,Breau, R., Fergusson, D., Skidmore, B., Wong, R., & Seely, D.
Publication: Integrative Cancer Therapies
Citedate: Tuesday, May 17, 2016
Citation: Integrative Cancer Therapies April-June 2016: 1–31
PMID: 27365385
Naturopathic Oncology Modified Delphi Panel
Authors:Hill, J., Hodsdon, W., Schor, J., McKinney, N., Rubin, D., Seely, D., Parmar, G., Birdsall, T., Alschuler, L., Lamson, D., Birdsall, S., & Zwickey, H.
Publication:Integrative Cancer Therapies
Citedate:July 24, 2015
Citation:Integr Cancer Ther. 2016 Mar;15(1):69-79.
PMID:26209468
Polysaccharide K and Coriolus versicolor Extracts for Lung Cancer: A Systematic Review
Authors: Fritz, H., Kennedy, D.A., Ishii, M., Fergusson, D., Fernandes, R., Cooley, K., & Seely, D.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine, The University of Toronto, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Centre
Citedate: Sunday, March 22, 2015
Citation: Integr Cancer Ther. 2015 Mar 17
PMID: 25784670
The Responsiveness, Content Validity, and Convergent Validity of the Measure Yourself Concerns and Wellbeing (MYCaW) Patient-Reported Outcome Measure
Authors: Jolliffe, R., Seers, H., Jackson, S., Caro, E., Weeks, L., & Polley, M.J.
Publication: Integrative Cancer Therapies
Affiliations: Penny Brohn Cancer Care, University of Granada, Ottawa Integrative Cancer Centre, University of Westminster
Citedate: Sunday, November 9, 2014
Citation: Integr Cancer Ther. 2015 Jan;14(1):26-34.
PMID: 25384697
Xenoestogens and breast cancer: chemical risk, exposure, and corporate power
Authors:Young, S., & Seely, D.
Publication:Our Chemical Selves: Gender, Toxics, and Environmental Health. (Edited by Dayna Nadine Scott. UBC Press.)
Citedate:2015
ISBN:978-0-7748-2834-5
Clinical Practice Guidelines on the Use of Integrative Cancer Therapies as Supportive Care in Patients Treated for Breast Cancer
Authors: Greenlee, H., Balneaves, L.G., Carlson, L.E., Cohen, M., Deng, G., Hershman, D., Mumber, M., Perlmutter, J., Seely, D., Sen, A., Zick, S.M., Tripathy, D. & Society for Integrative Oncology Guidelines Working Group
Publication: The Journal of the National Cancer Institute Monographs
Affiliations: Mailman School of Public Health, Herbert Irving Comprehensive Cancer Center, Department of Medicine, College of Physicians and Surgeons, Columbia University; University of British Columbia; University of Calgary; University of California San Francisco; C
Citedate: Friday, October 31, 2014
Citation: J Natl Cancer Inst Monogr (2014) 2014 (50): 346-358.
PMID: 25749602
Decision-making about complementary and alternative medicine by cancer patients: integrative literature review
Authors: Weeks, L., Balneaves, L.G., Paterson, C., Verhoef, M.
Publication: Open Medicine
Affiliations: Ottawa Integrative Cancer Centre, University of British Columbia, University of Bristol, University of Calgary
Citedate: Monday, April 14, 2014
Citation: Open Med. 2014 Apr 15;8(2):e54-66
PMID: 25009685
Developing an operational model for an integrative oncology program: a qualitative descriptive feasibility study
Authors: Weeks, L., Seely, D., DeGrasse, C., Verma, S., Boon, H., Verhoef, M., & Stacey, D.
Publication: Supportive Care In Cancer
Affiliations: Ottawa Integrative Cancer Centre
Citedate: Friday, February 28, 2014
Citation: Support Care Cancer. 2014 Mar;22(3):731-9.
PMID: 24221576
Intravenous Vitamin C and Cancer: A Systematic Review
Authors: Fritz, H., Flower, G., Weeks, L., Cooley, K., Callachan, M., McGowan, J., Skidmore, B., Kirchner, L., & Seely, D.
Publication: Integrative Cancer Therapies
Affiliations: The Canadian College of Naturopathic Mediicne, Ottawa Integrative Cancer Centre, University of Toronto, Carp Ridge Natural Health Clinic, Ottawa Hospital Research INstitute
Citedate: Tuesday, December 31, 2013
Citation: Integr Cancer Ther. 2014 May 26;13(4):280-300.
PMID: 24867961
Vitamin D: Pharmacokinetics and Safety When Used in Conjunction with the Pharmaceutical Drugs Used in Cancer Patients: A Systematic Review
Authors: Kennedy, D.A., Cooley, K., Skidmore, B., Fritz, H., Campbell, T. & Seely C.
Publication: Cancers
Affiliations: The Canadian College of Naturopathic Medicine, Ottawa Integrative Cancer Centre
Citedate: Monday, December 31, 2012
Citation: Cancers. 2013 Mar 11;5(1):255-80
PMID: 24216707
Black cohosh and breast cancer: a systematic review
Authors: Frtiz, H., Seely, D., McGowan, J., Skidmore, B., Fernandes, R., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Balneaves, L.G., & Fergusson, D.
Publication: Integrative Cancer Therapies
Affiliations: The Canadian College of Naturopathic Medicine, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Center, The University of Toronto, Toronto, Juravinski Cancer Center, McMaster University, University of British Columbia
Citedate: Monday, December 31, 2012
Citation: Integr Cancer Ther. 2014 Jan;13(1):12-29.
PMID: 23439657
Flax and breast cancer: a systematic review
Authors: Flower, G., Frtiz, H., Balneaves, L.G., Verma S, Skidmore, B., Fernandes, R., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Fergusson, D., & Seely, D.
Publication: Integrative Cancer Therapies
Affiliations: CCNM, University of British Columbia, CAMEO Program, McMaster University, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Centre
Citedate: Monday, December 31, 2012
Citation: Integr Cancer Ther. 2013 Sep 8;13(3):181-192.
PMID: 24013641
Canadian integrative oncology research priorities: results of a consensus-building process
Authors: Weeks, L.C., Seely, D., Balneaves, L.G., Boon, H.S., Leis, A., Oneschuk, D., Sagar, S.M., & Verhoef M.J.
Publication: Current Oncology
Affiliations: Ottawa Integrative Cancer Centre
Citedate: Monday, December 31, 2012
Citation: Curr Oncol. 2013 Aug;20(4):e289-99.
PMID: 23904767
Soy, Red Clover, and Isoflavones and Breast Cancer: A Systematic Review
Authors: Frtiz, H., Seely, D., Flower, G., Skidmore, B., Fernandes, R., Vadeboncoeur, S., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Sabri E, & Fergusson, D.
Publication: PLOS One
Affiliations: Canadian College of Naturopathic Medicine, Ottawa Integrative Cancer Centre, Ottawa Hospital Research Institute, McMaster University
Citedate: Monday, December 31, 2012
Citation: PLoS One. 2013 Nov 28;8(11):e81968.
PMID: 24312387
Green tea and lung cancer: a systematic review
Authors: Fritz, H., Seely, D., Kennedy, D.A., Fernandes, R., Cooley K., & Fergusson, D.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine, Hospital Research Institute, Ottawa Integrative Cancer Center, the University of Toronto
Citedate: Saturday, December 31, 2011
Citation: Frtiz, H., Seely, D., Kennedy, D.A., Fernandes, R., Cooley, K., Fergusson, D.. Green Tea and Lung Cancer: A Systematic Review. Integr Cancer Ther published online 24 April 2012
PMID: 22532034
A systematic review of integrative oncology programs
Authors: Seely, D., Weeks, L.C., & Young S.
Publication: Current Oncology
Affiliations: The Ottawa Integrative Cancer Centre
Citedate: Saturday, December 31, 2011
Citation: Curr Oncol. 2012 Dec;19(6):e436-61. doi: 10.3747/co.19.1182.
PMID: 23300368
Melatonin as Adjuvant Cancer Care With and Without Chemotherapy: A Systematic Review and Meta-analysis of Randomized Trials
Authors: Seely, D., Wu P., Frtiz, H., Kennedy, D.A., Tsui, T., Seely A., & Mills, E.
Publication: Integrative Cancer Therapies
Affiliations: The Canadian College of Naturopathic Medicine, Ottawa Integrative Cancer Center, Ottawa Hospital Research Institute
Citedate: Friday, December 31, 2010
Citation: Integr Cancer Ther. 2012 Dec;11(4):293-303.
PMID: 22019490
Selenium and lung cancer: a systematic review and meta analysis
Authors: Frtiz, H., Kennedy D, Fergusson, D., Fernandes, R., Cooley, K., Seely A, Sagar, S., Wong, R., & Seely, D.
Publication: PLOS One
Affiliations: Department of Research and Epidemiology, The Canadian College of Naturopathic Medicine, Leslie Dan Faculty of Pharmacy, The University of Toronto, Laboratory Medicine and Pathobiology (LMP)
Citedate: Friday, December 31, 2010
Citation: PLoS ONE 6(11): e26259. doi:10.1371/journal.pone.0026259
PMID: 22073154
Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis
Authors: Fritz, H. Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., & Seely D.
Publication: PLOS One
Affiliations: Department of Research and Epidemiology, The Canadian College of Naturopathic Medicine, Leslie Dan Faculty of Pharmacy, The University of Toronto, Laboratory Medicine and Pathobiology (LMP)
Citedate: Friday, December 31, 2010
Citation: PLoS One 2011; 6(6): e21107
PMID: 21738614
Astralagus-containing Chinese herbal combinations for advanced non-small-cell lung cancer: A meta-analysis of 65 clinical trials enrolling 4,751 patients
Authors: Dugoua, J.J., Wu, P., Seely, D., Eyawo, O., & Mills, E.
Publication: Lung Cancer: Targets and Therapy
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Thursday, December 31, 2009
Citation: Lung Cancer: Targets and Therapy 2010. 1:85-100
PMID:28210109
Shifting the paradigm: from complementary and alternative medicine (CAM) to integrative oncology
Authors: Leis, A., Sagar, S., Verhoef, M., Balneaves, L., Seely, D., & Oneschuk D.
Publication: Cancer Control. (Eedited by Elwood JM and Sutcliffe SB. Oxford University Press, Oxford, UK.)
Citedate: 2010
ISBN: 978-0-19-955017-3
A comparative review of thermography as a breast cancer screening technique
Authors: Kennedy, D., Lee, T., & Seely, D.
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Wednesday, December 31, 2008
Citation: Integrative Cancer Therapies 2009;8(1):9-16.
PMID: 19223370
Complementary Therapies. A guide for People with Cancer
Authors:Leis, A., Verhoef, M., Boon, H., Balneaves, L., Seely, D., Oneschuk, D., Sagar, S., & Weeks, L.
Publication: Booklet for the Canadian Cancer Society (through the CCAM Research Team)
Citedate: 2009
Patient decision-making about complementary and alternative medicine in cancer
Authors: Balneaves, LG.., Weeks, L., & Seely, D.
Publication: Current Oncology
Affiliations: University of British Columbia, Canadian College of Naturopathic Medicine
Citedate: Monday, December 31, 2007
Citation: Current Oncology, 2008;15 Suppl 2:s94-s100.
PMID: 18769576
Interactions of natural health products with biomedical cancer treatments
Authors: Seely D, Oneschuk D.
Publication: Current Oncology
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Monday, December 31, 2007
Citation: Current Oncology, 2008; 15 Suppl 2:s109.es81-10.es86.
PMID: 18769615
Integrative practices of Canadian oncology health professionals
Auhours: Brazier, A.S., Balneaves, L.G., Seely, D., Stephen, J.E., Suryaprakash, N., & Taylor-Brown, J.W.
Publication: Current Oncology
Affiliations: CAMEO Program, BC Cancer Agency
Citedate: Monday, December 31, 2007
Citation:Current Oncology, 2008 Aug;15 Suppl 2:s110.es87-91.
PMID: 18769573
A strategy for controlling potential interactions between natural health products and chemotherapy: a review in pediatric oncology
Authors: Seely, D., Stempak, D., & Baruchel, S.
Publication: Journal of Pediatric Hematology/Oncology
Affiliations: Hospital for Sick Children
Citedate: Sunday, December 31, 2006
Citation: Journal Pediatric Hematol Oncol, 2007;29(1):32-47.
PMID: 17230065
In vitro analysis of the herbal compound Essiac
Authors: Seely, D., Kennedy, D.A., Myers, S.P., Cheras, P.A., Lin, D., Li, R., Cattley, T., Brent, P.A., Mills, E., Leonard, B.J.
Publication: Anticancer Research
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Sunday, December 31, 2006
Citation: Anticancer Research, 2007;27(6B):3875-82.
PMID: 18225545
Flame Retardants and Cancer Risk
Authors: Seely, D., Fernandes, R., & Young, S.
Publication: Encyclopedia of Cancer and Society, edited by Graham A. Colditz. 3 vols. 1190p. Thousand Oaks, CA: Sage Publications
Citedate: 2007
ISBN: 978-1-4129-4989-7
Metronomic dosing of chemotherapy: applications in pediatric oncology
Authors: Stempak, D., Seely, D., & Baruchel, S.
Publication: Cancer Investigation
Affiliations: Hospital for Sick Children
Citedate: Saturday, December 31, 2005
Citation: Cancer Invest. 2006;24(4):432-43.
PMID: 16777697
An in vivo analysis of the herbal compound Essiac
Authors:Seely, D., Kennedy, D.A., Myers, S.P., Cheras, P.A., Lin, D., Li, R., Cattley, T., Brent, P.A., Mills, E., Leonard, B.J.
Publication: Anticancer Research
Affiliations:The Canadian College of Naturopathic Medicine
Citedate: Sunday, December 31, 2006
Citation: Anticancer Research, 2007;27(6B):3875-82.
PMID: 16886634
Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors
Authors: Mills, E.J., Seely, D., Rachlis, B., Griffith, L., Wu, P., Wilson, K., Ellis, P., & Wright, J.R.
Publication: Lancet Oncology
Affiliations: McMaster University, Canadian College of Naturopathic Medicine
Citedate: Saturday, December 31, 2005
Citation:Lancet Oncology, 2006;7(2):141-8.
PMID: 16455478
Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis
Authors: Mills. E., Wu, P., Seely, D., & Guyatt, G.
Publication: Journal of Pineal Research
Affiliations: McMaster University, Canadian College of Naturopathic Medicine
Citedate: Friday, December 31, 2004
Citation: Journal of Pineal Research 2005;39(4):360-6.
PMID: 16207291
The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review
Author: Seely, D., Mills, E.J., Wu, P., Verma, S., & Guyatt, G.H.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine
Citedate: Friday, December 31, 2004
Citation:Integr Cancer Ther. 2005;4(2):144-55.
PMID:15911927
Browse by Subject
Intravenous vitamin C in the supportive care of cancer patients: a review and rational approach
Intravenous Vitamin C and Cancer: A Systematic Review
Fish-Derived Omega-3 Fatty Acids and Prostate Cancer: A Systematic Review
Authors: Aucoin, M. , Cooley, K., Knee, C., Fritz, H., Balneaves, L.G.,Breau, R., Fergusson, D., Skidmore, B., Wong, R., & Seely, D.
Publication: Integrative Cancer Therapies
Citedate: Tuesday, May 17, 2016
Citation: Integrative Cancer Therapies April-June 2016: 1–31
PMID: 27365385
Polysaccharide K and Coriolus versicolor Extracts for Lung Cancer: A Systematic Review
Authors: Fritz, H., Kennedy, D.A., Ishii, M., Fergusson, D., Fernandes, R., Cooley, K., & Seely, D.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine, The University of Toronto, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Centre
Citedate: Sunday, March 22, 2015
Citation: Integr Cancer Ther. 2015 Mar 17
PMID: 25784670
Vitamin D: Pharmacokinetics and Safety When Used in Conjunction with the Pharmaceutical Drugs Used in Cancer Patients: A Systematic Review
Authors: Kennedy, D.A., Cooley, K., Skidmore, B., Fritz, H., Campbell, T. & Seely C.
Publication: Cancers
Affiliations: The Canadian College of Naturopathic Medicine, Ottawa Integrative Cancer Centre
Citedate: Monday, December 31, 2012
Citation: Cancers. 2013 Mar 11;5(1):255-80
PMID: 24216707
Black cohosh and breast cancer: a systematic review
Authors: Frtiz, H., Seely, D., McGowan, J., Skidmore, B., Fernandes, R., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Balneaves, L.G., & Fergusson, D.
Publication: Integrative Cancer Therapies
Affiliations: The Canadian College of Naturopathic Medicine, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Center, The University of Toronto, Toronto, Juravinski Cancer Center, McMaster University, University of British Columbia
Citedate: Monday, December 31, 2012
Citation: Integr Cancer Ther. 2014 Jan;13(1):12-29.
PMID: 23439657
Flax and breast cancer: a systematic review
Authors: Flower, G., Frtiz, H., Balneaves, L.G., Verma S, Skidmore, B., Fernandes, R., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Fergusson, D., & Seely, D.
Publication: Integrative Cancer Therapies
Affiliations: CCNM, University of British Columbia, CAMEO Program, McMaster University, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Centre
Citedate: Monday, December 31, 2012
Citation: Integr Cancer Ther. 2013 Sep 8;13(3):181-192.
PMID: 24013641
Soy, Red Clover, and Isoflavones and Breast Cancer: A Systematic Review
Authors: Frtiz, H., Seely, D., Flower, G., Skidmore, B., Fernandes, R., Vadeboncoeur, S., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Sabri E, & Fergusson, D.
Publication: PLOS One
Affiliations: Canadian College of Naturopathic Medicine, Ottawa Integrative Cancer Centre, Ottawa Hospital Research Institute, McMaster University
Citedate: Monday, December 31, 2012
Citation: PLoS One. 2013 Nov 28;8(11):e81968.
PMID: 24312387
Green tea and lung cancer: a systematic review
Authors: Fritz, H., Seely, D., Kennedy, D.A., Fernandes, R., Cooley K., & Fergusson, D.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine, Hospital Research Institute, Ottawa Integrative Cancer Center, the University of Toronto
Citedate: Saturday, December 31, 2011
Citation: Frtiz, H., Seely, D., Kennedy, D.A., Fernandes, R., Cooley, K., Fergusson, D.. Green Tea and Lung Cancer: A Systematic Review. Integr Cancer Ther published online 24 April 2012
PMID: 22532034
Melatonin as Adjuvant Cancer Care With and Without Chemotherapy: A Systematic Review and Meta-analysis of Randomized Trials
Authors: Seely, D., Wu P., Frtiz, H., Kennedy, D.A., Tsui, T., Seely A., & Mills, E.
Publication: Integrative Cancer Therapies
Affiliations: The Canadian College of Naturopathic Medicine, Ottawa Integrative Cancer Center, Ottawa Hospital Research Institute
Citedate: Friday, December 31, 2010
Citation: Integr Cancer Ther. 2012 Dec;11(4):293-303.
PMID: 22019490
Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis
Authors: Fritz, H. Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., & Seely D.
Publication: PLOS One
Affiliations: Department of Research and Epidemiology, The Canadian College of Naturopathic Medicine, Leslie Dan Faculty of Pharmacy, The University of Toronto, Laboratory Medicine and Pathobiology (LMP)
Citedate: Friday, December 31, 2010
Citation: PLoS One 2011; 6(6): e21107
PMID: 21738614
Selenium and lung cancer: a systematic review and meta analysis
Authors: Frtiz, H., Kennedy D, Fergusson, D., Fernandes, R., Cooley, K., Seely A, Sagar, S., Wong, R., & Seely, D.
Publication: PLOS One
Affiliations: Department of Research and Epidemiology, The Canadian College of Naturopathic Medicine, Leslie Dan Faculty of Pharmacy, The University of Toronto, Laboratory Medicine and Pathobiology (LMP)
Citedate: Friday, December 31, 2010
Citation: PLoS ONE 6(11): e26259. doi:10.1371/journal.pone.0026259
PMID: 22073154
Astralagus-containing Chinese herbal combinations for advanced non-small-cell lung cancer: A meta-analysis of 65 clinical trials enrolling 4,751 patients
Authors: Dugoua, J.J., Wu, P., Seely, D., Eyawo, O., & Mills, E.
Publication: Lung Cancer: Targets and Therapy
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Thursday, December 31, 2009
Citation: Lung Cancer: Targets and Therapy 2010. 1:85-100
PMID:28210109
Interactions of natural health products with biomedical cancer treatments
Authors: Seely D, Oneschuk D.
Publication: Current Oncology
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Monday, December 31, 2007
Citation: Current Oncology, 2008; 15 Suppl 2:s109.es81-10.es86.
PMID: 18769615
In vitro analysis of the herbal compound Essiac
Authors: Seely, D., Kennedy, D.A., Myers, S.P., Cheras, P.A., Lin, D., Li, R., Cattley, T., Brent, P.A., Mills, E., Leonard, B.J.
Publication: Anticancer Research
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Sunday, December 31, 2006
Citation: Anticancer Research, 2007;27(6B):3875-82.
PMID: 18225545
An in vivo analysis of the herbal compound Essiac
Authors: Seely, D., Kennedy, D.A., Myers, S.P., Cheras, P.A., Lin, D., Li, R., Cattley, T., Brent, P.A., Mills, E., Leonard, B.J.
Publication: Anticancer Research
Affiliations:The Canadian College of Naturopathic Medicine
Citedate: Sunday, December 31, 2006
Citation: Anticancer Research, 2007;27(6B):3875-82.
PMID: 16886634
Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis
Authors: Mills. E., Wu, P., Seely, D., & Guyatt, G.
Publication: Journal of Pineal Research
Affiliations: McMaster University, Canadian College of Naturopathic Medicine
Citedate: Friday, December 31, 2004
Citation: Journal of Pineal Research 2005;39(4):360-6.
PMID: 16207291
The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review
Author: Seely, D., Mills, E.J., Wu, P., Verma, S., & Guyatt, G.H.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine
Citedate: Friday, December 31, 2004
Citation: Integr Cancer Ther. 2005;4(2):144-55.
PMID: 15911927
A systematic review of acupuncture for chemotherapy-induced peripheral neuropathy
Authors: Li, K., Giustini, D., & Seely, D.
Publication: Current Oncology
Citedate: April 1, 2019
Citation: Curr Oncol. 2019 Apr;26(2):e147-e154.
PMID: 31043820
An N-of-1 Feasibility Study of Homeopathic Treatment for Fatigue in Patients Receiving Chemotherapy
Authors: Brulé, D., Balon, .J., Zhao, L., & Seely, D.
Publication:Homeopathy
Citedate: May 7, 2018
Citation:Homeopathy. 2018 Aug;107(3):196-201.
PMID: 29734461
Qualitative assessment of information and decision support needs for managing menopausal symptoms after breast cancer
Authors: Balneaves, L.G., Panagiotoglou, D., Brazier, A.S., Lambert, L.K., Porcino, A., Forbes, M., Van Patten, C., Truant, T.L., Seely, D., & Stacey, D.
Publication:Supportive Care in Cancer
Citedate: June 8, 2016
Citation:Support Care Cancer. 2016 Nov;24(11):4567-75.
PMID: 27278271
Complementary Therapies. A guide for People with Cancer
Authors: Leis, A., Verhoef, M., Boon, H., Balneaves, L., Seely, D., Oneschuk, D., Sagar, S., & Weeks, L.
Publication: booklet for the Canadian Cancer Society (through the CCAM Research Team)
Cietdate: 2009
Patient decision-making about complementary and alternative medicine in cancer
Authors: Balneaves, LG.., Weeks, L., & Seely, D.
Publication:Current Oncology
Affiliations:University of British Columbia, Canadian College of Naturopathic Medicine
Citedate: Monday, December 31, 2007
Citation:Current Oncology, 2008;15 Suppl 2:s94-s100.
PMID: 18769576
Personal goals of women recently diagnosed with breast cancer: Protocol for a cohort study
Authors: Chow, A.J., Fergusson, D.A., Seely, D., Young, S., Pitman, A., Ennis, J., Asad, S., Presseau, J.
Publication: University of Ottawa Journal of Medicine
Citedate: Dec 18, 2017
Citation: UOJM. Dec 2017; 7(2):34-41.
Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment
Authors: Greenlee, H., DuPont-Reyes, M.J., Balneaves, L.G., Carlson, L., Cohen, M.R., Deng, G., Johnson, J.A., Mumber, M., Seely, D., Zick, S.M., Boyce, L.M., & Tripathy, D.
Publication: A Cancer Journal for Clinicians
Citedate: April 24, 2017
Citation: CA Cancer J Clin. 67(3):194-232.
PMID: 28436999
Qualitative assessment of information and decision support needs for managing menopausal symptoms after breast cancer
Authors: Balneaves, L.G., Panagiotoglou, D., Brazier, A.S., Lambert, L.K., Porcino, A., Forbes, M., Van Patten, C., Truant, T.L., Seely, D., & Stacey, D.
Publication: Supportive Care in Cancer
Citedate: June 8, 2016
Citation: Support Care Cancer. 2016 Nov;24(11):4567-75.
PMID: 27278271
Clinical Practice Guidelines on the Use of Integrative Cancer Therapies as Supportive Care in Patients Treated for Breast Cancer
Authors: Greenlee, H., Balneaves, L.G., Carlson, L.E., Cohen, M., Deng, G., Hershman, D., Mumber, M., Perlmutter, J., Seely, D., Sen, A., Zick, S.M., Tripathy, D. & Society for Integrative Oncology Guidelines Working Group
Publication: The Journal of the National Cancer Institute Monographs
Affiliations: Mailman School of Public Health, Herbert Irving Comprehensive Cancer Center, Department of Medicine, College of Physicians and Surgeons, Columbia University; University of British Columbia; University of Calgary; University of California San Francisco; C
Citedate: Friday, October 31, 2014
Citation: J Natl Cancer Inst Monogr (2014) 2014 (50): 346-358.
PMID: 25749602
Black cohosh and breast cancer: a systematic review
Authors: Frtiz, H., Seely, D., McGowan, J., Skidmore, B., Fernandes, R., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Balneaves, L.G., & Fergusson, D.
Publication: Integrative Cancer Therapies
Affiliations: The Canadian College of Naturopathic Medicine, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Center, The University of Toronto, Toronto, Juravinski Cancer Center, McMaster University, University of British Columbia
Citedate: Monday, December 31, 2012
Citation: Integr Cancer Ther. 2014 Jan;13(1):12-29.
PMID: 23439657
Flax and breast cancer: a systematic review
Authors: Flower, G., Frtiz, H., Balneaves, L.G., Verma S, Skidmore, B., Fernandes, R., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Fergusson, D., & Seely, D.
Publication: Integrative Cancer Therapies
Affiliations: CCNM, University of British Columbia, CAMEO Program, McMaster University, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Centre
Citedate: Monday, December 31, 2012
Citation: Integr Cancer Ther. 2013 Sep 8;13(3):181-192.
PMID: 24013641
Soy, Red Clover, and Isoflavones and Breast Cancer: A Systematic Review
Authors: Frtiz, H., Seely, D., Flower, G., Skidmore, B., Fernandes, R., Vadeboncoeur, S., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Sabri E, & Fergusson, D.
Publication: PLOS One
Affiliations: Canadian College of Naturopathic Medicine, Ottawa Integrative Cancer Centre, Ottawa Hospital Research Institute, McMaster University
Citedate: Monday, December 31, 2012
Citation: PLoS One. 2013 Nov 28;8(11):e81968.
PMID: 24312387
Xenoestogens and breast cancer: chemical risk, exposure, and corporate power
Authors: Young, S., & Seely, D.
Publication: Our Chemical Selves: Gender, Toxics, and Environmental Health. (Edited by Dayna Nadine Scott. UBC Press.)
Citedate: 2015
ISBN: 978-0-7748-2834-5
A comparative review of thermography as a breast cancer screening technique
Authors: Kennedy, D., Lee, T., & Seely, D.
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Wednesday, December 31, 2008
Citation: Integrative Cancer Therapies 2009;8(1):9-16.
PMID: 19223370
The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review
Author: Seely, D., Mills, E.J., Wu, P., Verma, S., & Guyatt, G.H.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine
Citedate: Friday, December 31, 2004
Citation: Integr Cancer Ther. 2005;4(2):144-55.
PMID: 15911927
Polysaccharide K and Coriolus versicolor Extracts for Lung Cancer: A Systematic Review
Authors: Fritz, H., Kennedy, D.A., Ishii, M., Fergusson, D., Fernandes, R., Cooley, K., & Seely, D.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine, The University of Toronto, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Centre
Citedate: Sunday, March 22, 2015
Citation: Integr Cancer Ther. 2015 Mar 17
PMID: 25784670
Selenium and lung cancer: a systematic review and meta analysis
Authors: Frtiz, H., Kennedy D, Fergusson, D., Fernandes, R., Cooley, K., Seely A, Sagar, S., Wong, R., & Seely, D.
Publication: PLOS One
Affiliations: Department of Research and Epidemiology, The Canadian College of Naturopathic Medicine, Leslie Dan Faculty of Pharmacy, The University of Toronto, Laboratory Medicine and Pathobiology (LMP)
Citedate: Friday, December 31, 2010
Citation: PLoS ONE 6(11): e26259. doi:10.1371/journal.pone.0026259
PMID: 22073154
Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis
Authors: Fritz, H. Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., & Seely D.
Publication: PLOS One
Affiliations: Department of Research and Epidemiology, The Canadian College of Naturopathic Medicine, Leslie Dan Faculty of Pharmacy, The University of Toronto, Laboratory Medicine and Pathobiology (LMP)
Citedate: Friday, December 31, 2010
Citation: PLoS One 2011; 6(6): e21107
PMID: 21738614
Astralagus-containing Chinese herbal combinations for advanced non-small-cell lung cancer: A meta-analysis of 65 clinical trials enrolling 4,751 patients
Authors: Dugoua, J.J., Wu, P., Seely, D., Eyawo, O., & Mills, E.
Publication:Lung Cancer: Targets and Therapy
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Thursday, December 31, 2009
Citation: Lung Cancer: Targets and Therapy 2010. 1:85-100
PMID: 28210109
Green tea and lung cancer: a systematic review
Authors: Fritz, H., Seely, D., Kennedy, D.A., Fernandes, R., Cooley K., & Fergusson, D.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine, Hospital Research Institute, Ottawa Integrative Cancer Center, the University of Toronto
Citedate: Saturday, December 31, 2011
Citation: Frtiz, H., Seely, D., Kennedy, D.A., Fernandes, R., Cooley, K., Fergusson, D.. Green Tea and Lung Cancer: A Systematic Review. Integr Cancer Ther published online 24 April 2012
PMID: 22532034
A strategy for controlling potential interactions between natural health products and chemotherapy: a review in pediatric oncology
Authors: Seely, D., Stempak, D., & Baruchel, S.
Publication: Journal of Pediatric Hematology/Oncology
Affiliations: Hospital for Sick Children
Citedate: Sunday, December 31, 2006
Citation: Journal Pediatric Hematol Oncol, 2007;29(1):32-47.
PMID: 17230065
Metronomic dosing of chemotherapy: applications in pediatric oncology
Authors: Stempak, D., Seely, D., & Baruchel, S.
Publication: Cancer Investigation
Affiliations: Hospital for Sick Children
Citedate: Saturday, December 31, 2005
Citation:Cancer Invest. 2006;24(4):432-43.
PMID: 16777697
Browse by Methodology
Intravenous vitamin C in the supportive care of cancer patients: a review and rational approach
Authors: Klimant, E., Wright, H., D. Rubin, Seely, D. & Markman, M.
Publication: Current Oncology
Citedate: Monday, April 30, 2018
Citation: Curr Oncol. 2018 Apr; 25(2): 139–148.
PMID: 29719430
Decision-making about complementary and alternative medicine by cancer patients: integrative literature review
Authors: Weeks, L., Balneaves, L.G., Paterson, C., Verhoef, M.
Publication: Open Medicine
Affiliations: Ottawa Integrative Cancer Centre, University of British Columbia, University of Bristol, University of Calgary
Citedate: Monday, April 14, 2014
Citation: Open Med. 2014 Apr 15;8(2):e54-66
PMID: 25009685
A comparative review of thermography as a breast cancer screening technique
Authors: Kennedy, D., Lee, T., & Seely, D.
Affiliations:The Canadian College of Naturopathic Medicine
Citedate: Wednesday, December 31, 2008
Citation: Integrative Cancer Therapies 2009;8(1):9-16.
PMID: 19223370
A strategy for controlling potential interactions between natural health products and chemotherapy: a review in pediatric oncology
Authors:Seely, D., Stempak, D., & Baruchel, S.
Publication: Journal of Pediatric Hematology/Oncology
Affiliations: Hospital for Sick Children
Citedate: Sunday, December 31, 2006
Citation:Journal Pediatric Hematol Oncol, 2007;29(1):32-47.
PMID: 17230065
A systematic review of acupuncture for chemotherapy-induced peripheral neuropathy
Authors: Li, K., Giustini, D., & Seely, D.
Publication: Current Oncology
Citedate: April 1, 2019
Citation: Curr Oncol. 2019 Apr;26(2):e147-e154.
PMID: 31043820
Fish-Derived Omega-3 Fatty Acids and Prostate Cancer: A Systematic Review
Authors: Aucoin, M. , Cooley, K., Knee, C., Fritz, H., Balneaves, L.G.,Breau, R., Fergusson, D., Skidmore, B., Wong, R., & Seely, D.
Publication: Integrative Cancer Therapies
Citedate: Tuesday, May 17, 2016
Citation: Integrative Cancer Therapies April-June 2016: 1–31
PMID: 27365385
Polysaccharide K and Coriolus versicolor Extracts for Lung Cancer: A Systematic Review
Authors: Fritz, H., Kennedy, D.A., Ishii, M., Fergusson, D., Fernandes, R., Cooley, K., & Seely, D.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine, The University of Toronto, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Centre
Citedate: Sunday, March 22, 2015
Citation: Integr Cancer Ther. 2015 Mar 17
PMID: 25784670
Intravenous Vitamin C and Cancer: A Systematic Review
Authors: Fritz, H., Flower, G., Weeks, L., Cooley, K., Callachan, M., McGowan, J., Skidmore, B., Kirchner, L., & Seely, D.
Publication: Integrative Cancer Therapies
Affiliations: The Canadian College of Naturopathic Mediicne, Ottawa Integrative Cancer Centre, University of Toronto, Carp Ridge Natural Health Clinic, Ottawa Hospital Research INstitute
Citedate: Tuesday, December 31, 2013
Citation: Integr Cancer Ther. 2014 May 26;13(4):280-300.
PMID: 24867961
Vitamin D: Pharmacokinetics and Safety When Used in Conjunction with the Pharmaceutical Drugs Used in Cancer Patients: A Systematic Review
Authors: Kennedy, D.A., Cooley, K., Skidmore, B., Fritz, H., Campbell, T. & Seely C.
Publication: Cancers
Affiliations: The Canadian College of Naturopathic Medicine, Ottawa Integrative Cancer Centre
Citedate: Monday, December 31, 2012
Citation: Cancers. 2013 Mar 11;5(1):255-80
PMID: 24216707
Black cohosh and breast cancer: a systematic review
Authors: Frtiz, H., Seely, D., McGowan, J., Skidmore, B., Fernandes, R., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Balneaves, L.G., & Fergusson, D.
Publication: Integrative Cancer Therapies
Affiliations: The Canadian College of Naturopathic Medicine, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Center, The University of Toronto, Toronto, Juravinski Cancer Center, McMaster University, University of British Columbia
Citedate: Monday, December 31, 2012
Citation: Integr Cancer Ther. 2014 Jan;13(1):12-29.
PMID: 23439657
Flax and breast cancer: a systematic review
Authors: Flower, G., Frtiz, H., Balneaves, L.G., Verma S, Skidmore, B., Fernandes, R., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Fergusson, D., & Seely, D.
Publication: Integrative Cancer Therapies
Affiliations: CCNM, University of British Columbia, CAMEO Program, McMaster University, Ottawa Hospital Research Institute, Ottawa Integrative Cancer Centre
Citedate: Monday, December 31, 2012
Citation: Integr Cancer Ther. 2013 Sep 8;13(3):181-192.
PMID: 24013641
Soy, Red Clover, and Isoflavones and Breast Cancer: A Systematic Review
Authors: Frtiz, H., Seely, D., Flower, G., Skidmore, B., Fernandes, R., Vadeboncoeur, S., Kennedy, D.A., Cooley, K., Wong, R., Sagar, S., Sabri E, & Fergusson, D.
Publication: PLOS One
Affiliations: Canadian College of Naturopathic Medicine, Ottawa Integrative Cancer Centre, Ottawa Hospital Research Institute, McMaster University
Citedate: Monday, December 31, 2012
Citation: PLoS One. 2013 Nov 28;8(11):e81968.
PMID: 24312387
Green tea and lung cancer: a systematic review
Authors: Fritz, H., Seely, D., Kennedy, D.A., Fernandes, R., Cooley K., & Fergusson, D.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine, Hospital Research Institute, Ottawa Integrative Cancer Center, the University of Toronto
Citedate: Saturday, December 31, 2011
Citation: Frtiz, H., Seely, D., Kennedy, D.A., Fernandes, R., Cooley, K., Fergusson, D.. Green Tea and Lung Cancer: A Systematic Review. Integr Cancer Ther published online 24 April 2012
PMID: 22532034
A systematic review of integrative oncology programs
Authors: Seely, D., Weeks, L.C., & Young S.
Publication: Current Oncology
Affiliations: The Ottawa Integrative Cancer Centre
Citedate: Saturday, December 31, 2011
Citation: Curr Oncol. 2012 Dec;19(6):e436-61. doi: 10.3747/co.19.1182.
PMID: 23300368
Melatonin as Adjuvant Cancer Care With and Without Chemotherapy: A Systematic Review and Meta-analysis of Randomized Trials
Authors: Seely, D., Wu P., Frtiz, H., Kennedy, D.A., Tsui, T., Seely A., & Mills, E.
Publication: Integrative Cancer Therapies
Affiliations: The Canadian College of Naturopathic Medicine, Ottawa Integrative Cancer Center, Ottawa Hospital Research Institute
Citedate: Friday, December 31, 2010
Citation: Integr Cancer Ther. 2012 Dec;11(4):293-303.
PMID: 22019490
Selenium and lung cancer: a systematic review and meta analysis
Authors: Frtiz, H., Kennedy D, Fergusson, D., Fernandes, R., Cooley, K., Seely A, Sagar, S., Wong, R., & Seely, D.
Publication: PLOS One
Affiliations: Department of Research and Epidemiology, The Canadian College of Naturopathic Medicine, Leslie Dan Faculty of Pharmacy, The University of Toronto, Laboratory Medicine and Pathobiology (LMP)
Citedate: Friday, December 31, 2010
Citation: PLoS ONE 6(11): e26259. doi:10.1371/journal.pone.0026259
PMID: 22073154
Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis
Authors: Fritz, H. Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., & Seely D.
Publication: PLOS One
Affiliations: Department of Research and Epidemiology, The Canadian College of Naturopathic Medicine, Leslie Dan Faculty of Pharmacy, The University of Toronto, Laboratory Medicine and Pathobiology (LMP)
Citedate: Friday, December 31, 2010
Citation: PLoS One 2011; 6(6): e21107
PMID: 21738614
Astralagus-containing Chinese herbal combinations for advanced non-small-cell lung cancer: A meta-analysis of 65 clinical trials enrolling 4,751 patients
Authors: Dugoua, J.J., Wu, P., Seely, D., Eyawo, O., & Mills, E.
Publication: Lung Cancer: Targets and Therapy
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Thursday, December 31, 2009
Citation: Lung Cancer: Targets and Therapy 2010. 1:85-100
PMID: 28210109
Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors
Authors: Mills, E.J., Seely, D., Rachlis, B., Griffith, L., Wu, P., Wilson, K., Ellis, P., & Wright, J.R.
Publication: Lancet Oncology
Affiliations: McMaster University, Canadian College of Naturopathic Medicine
Citedate: Saturday, December 31, 2005
Citation: Lancet Oncology, 2006;7(2):141-8.
PMID: 16455478
Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis
Authors: Mills. E., Wu, P., Seely, D., & Guyatt, G.
Publication: Journal of Pineal Research
Affiliations: McMaster University, Canadian College of Naturopathic Medicine
Citedate: Friday, December 31, 2004
Citation: Journal of Pineal Research 2005;39(4):360-6.
PMID: 16207291
The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review
Author: Seely, D., Mills, E.J., Wu, P., Verma, S., & Guyatt, G.H.
Publication: Integrative Cancer Therapies
Affiliations: Canadian College of Naturopathic Medicine
Citedate: Friday, December 31, 2004
Citation: Integr Cancer Ther. 2005;4(2):144-55.
PMID: 15911927
Intervention Development Process for a Pragmatic Randomized Controlled Trial: The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial
Authors: Seely, D., Ennis, J.E., McDonell, E., et al.
Publication: Journal of Alternative and Complementary Medicine
Citedate: March 19, 2019
Citation: J Altern Complement Med. 2019;25(S1):S112-S123.
PMID: 30870012
Naturopathic Oncology Care for Thoracic Cancers: A Practice Survey
Authors: Seely, D., Ennis J.K., McDonell, E., & Zhao. L.
Publication: Integrative Cancer Therapies
Citedate: Monday, December 18, 2017
Citation:Integr Cancer Ther. 2018;17(3).
PMID: 29558830
An N-of-1 Feasibility Study of Homeopathic Treatment for Fatigue in Patients Receiving Chemotherapy
Authors: Brulé, D., Balon, .J., Zhao, L., & Seely, D.
Publication: Homeopathy
Citedate: May 7, 2018
Citation: Homeopathy. 2018 Aug;107(3):196-201.
PMID: 29734461
Developing an operational model for an integrative oncology program: a qualitative descriptive feasibility study
Authors: Weeks, L., Seely, D., DeGrasse, C., Verma, S., Boon, H., Verhoef, M., & Stacey, D.
Publication: Supportive Care In Cancer
Affiliations: Ottawa Integrative Cancer Centre
Citedate: Friday, February 28, 2014
Citation: Support Care Cancer. 2014 Mar;22(3):731-9.
PMID: 24221576
In vitro analysis of the herbal compound Essiac
Authors: Seely, D., Kennedy, D.A., Myers, S.P., Cheras, P.A., Lin, D., Li, R., Cattley, T., Brent, P.A., Mills, E., Leonard, B.J.
Publication: Anticancer Research
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Sunday, December 31, 2006
Citation: Anticancer Research, 2007;27(6B):3875-82.
PMID: 18225545
Editorial: The Oncology Association of Naturopathic Physicians Principles of Care Guidelines
Authors: Seely, D., & Verma, S.
Publication: Current Oncology
Citedate: February 1, 2019
Citation: Curr Oncol. 2019. Vol 26, No 1.
PMID: 30853791
Integrative Oncology: International Perspectives
Authors: Grant, S.J., Hunter, J., Seely, D., Balneaves, L.G., Rossi, E., & Bao, T.
Publication: Integrative Cancer Therapies
Citedate: January 30, 2019
Citation: Integr Cancer Ther. 2019. Jan-Dec;18
PMID: 30791736
Personal goals of women recently diagnosed with breast cancer: Protocol for a cohort study
Authors: Chow, A.J., Fergusson, D.A., Seely, D., Young, S., Pitman, A., Ennis, J., Asad, S., Presseau, J.
Publication: University of Ottawa Journal of Medicine
Citedate: Dec 18, 2017
Citation: UOJM. Dec 2017; 7(2):34-41.
Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment
Authors: Greenlee, H., DuPont-Reyes, M.J., Balneaves, L.G., Carlson, L., Cohen, M.R., Deng, G., Johnson, J.A., Mumber, M., Seely, D., Zick, S.M., Boyce, L.M., & Tripathy, D.
Publication: A Cancer Journal for Clinicians
Citedate: April 24, 2017
Citation: CA Cancer J Clin. 67(3):194-232.
PMID: 28436999
Qualitative assessment of information and decision support needs for managing menopausal symptoms after breast cancer
Authors: Balneaves, L.G., Panagiotoglou, D., Brazier, A.S., Lambert, L.K., Porcino, A., Forbes, M., Van Patten, C., Truant, T.L., Seely, D., & Stacey, D.
Publication: Supportive Care in Cancer
Citedate: June 8, 2016
Citation: Support Care Cancer. 2016 Nov;24(11):4567-75.
PMID: 27278271
Naturopathic Oncology Modified Delphi Panel
Authors: Hill, J., Hodsdon, W., Schor, J., McKinney, N., Rubin, D., Seely, D., Parmar, G., Birdsall, T., Alschuler, L., Lamson, D., Birdsall, S., & Zwickey, H.
Publication: Integrative Cancer Therapies
Citedate: July 24, 2015
Citation: Integr Cancer Ther. 2016 Mar;15(1):69-79.
PMID: 26209468
The Responsiveness, Content Validity, and Convergent Validity of the Measure Yourself Concerns and Wellbeing (MYCaW) Patient-Reported Outcome Measure
Authors: Jolliffe, R., Seers, H., Jackson, S., Caro, E., Weeks, L., & Polley, M.J.
Publication: Integrative Cancer Therapies
Affiliations: Penny Brohn Cancer Care, University of Granada, Ottawa Integrative Cancer Centre, University of Westminster
Citedate: Sunday, November 9, 2014
Citation: Integr Cancer Ther. 2015 Jan;14(1):26-34.
PMID: 25384697
Xenoestogens and breast cancer: chemical risk, exposure, and corporate power
Authors:Young, S., & Seely, D.
Publication:Our Chemical Selves: Gender, Toxics, and Environmental Health. (Edited by Dayna Nadine Scott. UBC Press.)
Citedate:2015
ISBN:978-0-7748-2834-5
Clinical Practice Guidelines on the Use of Integrative Cancer Therapies as Supportive Care in Patients Treated for Breast Cancer
Authors: Greenlee, H., Balneaves, L.G., Carlson, L.E., Cohen, M., Deng, G., Hershman, D., Mumber, M., Perlmutter, J., Seely, D., Sen, A., Zick, S.M., Tripathy, D. & Society for Integrative Oncology Guidelines Working Group
Publication: The Journal of the National Cancer Institute Monographs
Affiliations: Mailman School of Public Health, Herbert Irving Comprehensive Cancer Center, Department of Medicine, College of Physicians and Surgeons, Columbia University; University of British Columbia; University of Calgary; University of California San Francisco; C
Citedate: Friday, October 31, 2014
Citation: J Natl Cancer Inst Monogr (2014) 2014 (50): 346-358.
PMID: 25749602
Canadian integrative oncology research priorities: results of a consensus-building process
Authors: Weeks, L.C., Seely, D., Balneaves, L.G., Boon, H.S., Leis, A., Oneschuk, D., Sagar, S.M., & Verhoef M.J.
Publication: Current Oncology
Affiliations: Ottawa Integrative Cancer Centre
Citedate: Monday, December 31, 2012
Citation: Curr Oncol. 2013 Aug;20(4):e289-99.
PMID: 23904767
Shifting the paradigm: from complementary and alternative medicine (CAM) to integrative oncology
Authors: Leis, A., Sagar, S., Verhoef, M., Balneaves, L., Seely, D., & Oneschuk D.
Publication: Cancer Control. (Eedited by Elwood JM and Sutcliffe SB. Oxford University Press, Oxford, UK.)
Citedate: 2010
ISBN: 978-0-19-955017-3
Patient decision-making about complementary and alternative medicine in cancer
Authors: Balneaves, LG.., Weeks, L., & Seely, D.
Publication: Current Oncology
Affiliations: University of British Columbia, Canadian College of Naturopathic Medicine
Citedate: Monday, December 31, 2007
Citation: Current Oncology, 2008;15 Suppl 2:s94-s100.
PMID: 18769576
Interactions of natural health products with biomedical cancer treatments
Authors: Seely D, Oneschuk D.
Publication: Current Oncology
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Monday, December 31, 2007
Citation: Current Oncology, 2008; 15 Suppl 2:s109.es81-10.es86.
PMID: 18769615
Integrative practices of Canadian oncology health professionals
Auhours: Brazier, A.S., Balneaves, L.G., Seely, D., Stephen, J.E., Suryaprakash, N., & Taylor-Brown, J.W.
Publication: Current Oncology
Affiliations: CAMEO Program, BC Cancer Agency
Citedate: Monday, December 31, 2007
Citation: Current Oncology, 2008 Aug;15 Suppl 2:s110.es87-91.
PMID: 18769573
Flame Retardants and Cancer Risk
Authors: Seely, D., Fernandes, R., & Young, S.
Publication: Encyclopedia of Cancer and Society, edited by Graham A. Colditz. 3 vols. 1190p. Thousand Oaks, CA: Sage Publications
Citedate: 2007
ISBN: 978-1-4129-4989-7
Metronomic dosing of chemotherapy: applications in pediatric oncology
Authors: Stempak, D., Seely, D., & Baruchel, S.
Publication: Cancer Investigation
Affiliations: Hospital for Sick Children
Citedate: Saturday, December 31, 2005
Citation: Cancer Invest. 2006;24(4):432-43.
PMID: 16777697
An in vivo analysis of the herbal compound Essiac
Authors: Seely, D., Kennedy, D.A., Myers, S.P., Cheras, P.A., Lin, D., Li, R., Cattley, T., Brent, P.A., Mills, E., Leonard, B.J.
Publication: Anticancer Research
Affiliations: The Canadian College of Naturopathic Medicine
Citedate: Sunday, December 31, 2006
Citation: Anticancer Research, 2007;27(6B):3875-82.
PMID: 16886634
Research Funders
The OICC gratefully acknowledges support of our research funders.
The primary goal of the Canadian Complementary and Alternative Medicine Research Fund (CCRF) is to increase and enhance complementary medicine research capacity in Canada by supporting and funding relevant and high caliber studies. Funding through the CCRF has being used to support two studies: 1) Towards Integrative Cancer Care: A Participatory, Formative Evaluation of Practitioner Integration at the Ottawa Integrative Cancer Centre; and 2) An n-of-1 study of homeopathic treatment of fatigue in patients receiving chemotherapy.
The Canadian Institutes of Health Research (CIHR) is the Government of Canada’s premier agency for health research. Funding through the CIHR has being used to support OICC efforts towards: Developing a Community-Based Integrative Oncology Research Program. CIHR funding has also helped support two large scale synthesis reviews on natural health products used by people with lung and breast cancer respectively and led to a number of open access publications.
Since their beginning nearly 20 years ago, the Gateway for Cancer Research has sought better treatment options for cancer patients—options that extend life, improve quality of life, and strive to cure people.
One of the Lotte and John Hecht Memorial Foundation's two major objectives is to support the investigation and support of complementary and alternative medicine, particularly in the treatment of cancer. Funding through the Lotte and John Hecht Memorial Foundation initially supported a multi-phase feasibility study that informed the development of the OICC model. In addition, the Hecht foundation is the main supporter of the multi-site Canadian trial, the Adjuvant Melatonin in the Prevention of Recurrence and Mortality Following Lung Cancer Resection: A Randomized Placebo Controlled Clinical Trial (AMPLCaRe). Their support is also behind two of the major research projects that the OICC is running including CUSIOS and TPOISE.
INCAM is a collaborative and interdisciplinary research community in Canada generating knowledge through research on complementary, alternative, and integrative medicine/health care* to enhance the health of Canadians.
Since its launch in 2004, INCAM has been instrumental in defining a CAM research community in Canada. Today, INCAM is the place to go for researchers, educators and practitioners who are interested in research which aims to address challenging questions in innovative ways in this emerging area of practice and research.
